Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane

Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no available detailed data on its permeation in in vitro c...

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Detalles Bibliográficos
Autores principales: Kus, Marta, Gorniak, Klaudia, Czaklosz, Piotr, Olejnik, Anna, Skupin-Mrugalska, Paulina, Ibragimow, Izabela, Piotrowska-Kempisty, Hanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000469/
https://www.ncbi.nlm.nih.gov/pubmed/35408631
http://dx.doi.org/10.3390/molecules27072232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000469/
https://www.ncbi.nlm.nih.gov/pubmed/35408631
http://dx.doi.org/10.3390/molecules27072232

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