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Permeability of the Perindopril Arginine under In Vitro Conditions across Caco-2 Monolayer and Biomimetic Phospholipid Membrane
Perindopril arginine (PA) as an angiotensin-converting enzyme (ACE) inhibitor is widely used in cardiovascular diseases, especially in systemic hypertension and heart failure. Although the pharmacokinetics of PA are well documented, there is no available detailed data on its permeation in in vitro c...
Autores principales: | Kus, Marta, Gorniak, Klaudia, Czaklosz, Piotr, Olejnik, Anna, Skupin-Mrugalska, Paulina, Ibragimow, Izabela, Piotrowska-Kempisty, Hanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000469/ https://www.ncbi.nlm.nih.gov/pubmed/35408631 http://dx.doi.org/10.3390/molecules27072232 |
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