Cardiorenal Protective Effect of Costunolide against Doxorubicin-Induced Toxicity in Rats by Modulating Oxidative Stress, Inflammation and Apoptosis

Doxorubicin (DXB) is one of the most commonly used anticancer agents for treating solid and hematological malignancies; however, DXB-induced cardiorenal toxicity presents a limiting factor to its clinical usefulness in cancer patients. Costunolide (COST) is a naturally occurring sesquiterpene lacton...

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Detalles Bibliográficos
Autores principales: Xing, Wen, Wen, Chaoling, Wang, Deguo, Shao, Hui, Liu, Chunhong, He, Chunling, Olatunji, Opeyemi Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000510/
https://www.ncbi.nlm.nih.gov/pubmed/35408518
http://dx.doi.org/10.3390/molecules27072122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000510/
https://www.ncbi.nlm.nih.gov/pubmed/35408518
http://dx.doi.org/10.3390/molecules27072122

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