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Gating Mechanism of the Voltage-Gated Proton Channel Studied by Molecular Dynamics Simulations

The voltage-gated proton channel Hv1 has important roles in proton extrusion, pH homeostasis, sperm motility, and cancer progression. The Hv1 channel has also been found to be highly expressed in cell lines and tissue samples from patients with breast cancer. A high-resolution closed-state structure...

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Detalles Bibliográficos
Autores principales: Phan, Thi Tuong Vy, Yi, Myunggi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000549/
https://www.ncbi.nlm.nih.gov/pubmed/35408673
http://dx.doi.org/10.3390/molecules27072277