Target Design of Novel Histone Deacetylase 6 Selective Inhibitors with 2-Mercaptoquinazolinone as the Cap Moiety

Epigenetic alterations found in all human cancers are promising targets for anticancer therapy. In this sense, histone deacetylase inhibitors (HDACIs) are interesting anticancer agents that play an important role in the epigenetic regulation of cancer cells. Here, we report 15 novel hydroxamic acid-...

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Detalles Bibliográficos
Autores principales: Bui, Hue Thi Buu, Nguyen, Phuong Hong, Pham, Quan Minh, Tran, Hoa Phuong, Tran, De Quang, Jung, Hosun, Hong, Quang Vinh, Nguyen, Quoc Cuong, Nguyen, Quy Phu, Le, Hieu Trong, Yang, Su-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000625/
https://www.ncbi.nlm.nih.gov/pubmed/35408604
http://dx.doi.org/10.3390/molecules27072204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000625/
https://www.ncbi.nlm.nih.gov/pubmed/35408604
http://dx.doi.org/10.3390/molecules27072204

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