Efficient Synthesis of Acylated, Dialkyl α-Hydroxy-Benzylphosphonates and Their Anticancer Activity

An efficient method applying acyl chlorides as reagents was developed for the acylation of the hindered hydroxy group of dialkyl α-hydroxy-benzylphosphonates. The procedure did not require any catalyst. A few acylations were also performed with the S(C)-enantiomer of dimethyl α-hydroxy-benzylphospho...

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Detalles Bibliográficos
Autores principales: Varga, Petra R., Belovics, Alexandra, Bagi, Péter, Tóth, Szilárd, Szakács, Gergely, Bősze, Szilvia, Szabó, Rita, Drahos, László, Keglevich, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000670/
https://www.ncbi.nlm.nih.gov/pubmed/35408466
http://dx.doi.org/10.3390/molecules27072067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000670/
https://www.ncbi.nlm.nih.gov/pubmed/35408466
http://dx.doi.org/10.3390/molecules27072067

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