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Efficient Synthesis of Acylated, Dialkyl α-Hydroxy-Benzylphosphonates and Their Anticancer Activity
An efficient method applying acyl chlorides as reagents was developed for the acylation of the hindered hydroxy group of dialkyl α-hydroxy-benzylphosphonates. The procedure did not require any catalyst. A few acylations were also performed with the S(C)-enantiomer of dimethyl α-hydroxy-benzylphospho...
Autores principales: | Varga, Petra R., Belovics, Alexandra, Bagi, Péter, Tóth, Szilárd, Szakács, Gergely, Bősze, Szilvia, Szabó, Rita, Drahos, László, Keglevich, György |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000670/ https://www.ncbi.nlm.nih.gov/pubmed/35408466 http://dx.doi.org/10.3390/molecules27072067 |
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