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Phosphorylation of cPLA(2)α at Ser(505) Is Necessary for Its Translocation to PtdInsP(2)-Enriched Membranes
Group IVA cytosolic phospholipase A(2)α (cPLA(2)α) is a key enzyme in physiology and pathophysiology because it constitutes a rate-limiting step in the pathway for the generation of pro- and anti-inflammatory eicosanoid lipid mediators. cPLA(2)α activity is tightly regulated by multiple factors, inc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000823/ https://www.ncbi.nlm.nih.gov/pubmed/35408744 http://dx.doi.org/10.3390/molecules27072347 |