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Isolation of a Melanoblast Stimulator from Dimocarpus longan, Its Structural Modification, and Structure–Activity Relationships for Vitiligo

A novel melanoblast stimulator (1) was isolated from Dimocarpus longan. Its analogs were also synthesized to support a new furan-based melanoblast stimulator scaffold for treating vitiligo. Isolated 5-(hydroxymethyl)furfural (HMF, 1) is a well-known compound in the food industry. Surprisingly, the m...

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Detalles Bibliográficos
Autores principales: Song, Jae-Won, Choi, Sunju, Kim, Gayeong, Lee, Hyang Bok, Rao, P. Sankara, Shin, Jeonghyun, Kim, Eun Ki, Cho, Dong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000856/
https://www.ncbi.nlm.nih.gov/pubmed/35408531
http://dx.doi.org/10.3390/molecules27072135