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Isolation of a Melanoblast Stimulator from Dimocarpus longan, Its Structural Modification, and Structure–Activity Relationships for Vitiligo
A novel melanoblast stimulator (1) was isolated from Dimocarpus longan. Its analogs were also synthesized to support a new furan-based melanoblast stimulator scaffold for treating vitiligo. Isolated 5-(hydroxymethyl)furfural (HMF, 1) is a well-known compound in the food industry. Surprisingly, the m...
Autores principales: | Song, Jae-Won, Choi, Sunju, Kim, Gayeong, Lee, Hyang Bok, Rao, P. Sankara, Shin, Jeonghyun, Kim, Eun Ki, Cho, Dong-Gyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000856/ https://www.ncbi.nlm.nih.gov/pubmed/35408531 http://dx.doi.org/10.3390/molecules27072135 |
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