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Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2

This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar moieties and modified analogues. All the newly synthesized derivatives were screened for their cytotoxic activities against a panel of human...

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Detalles Bibliográficos
Autores principales: El-Sayed, Wael A., Alminderej, Fahad M., Mounier, Marwa M., Nossier, Eman S., Saleh, Sayed M., Kassem, Asmaa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000887/
https://www.ncbi.nlm.nih.gov/pubmed/35408446
http://dx.doi.org/10.3390/molecules27072047