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Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates

Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia coli transporter, EmrE, has been studied extensivel...

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Detalles Bibliográficos
Autores principales: Kermani, Ali A, Burata, Olive E, Koff, B Ben, Koide, Akiko, Koide, Shohei, Stockbridge, Randy B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000954/
https://www.ncbi.nlm.nih.gov/pubmed/35254261
http://dx.doi.org/10.7554/eLife.76766