Pin1 aggravates renal injury induced by ischemia and reperfusion in rats via Nrf2/HO-1 mediated endoplasmic reticulum stress

PURPOSE: To investigate the role of peptidyl-prolyl cis/trans isomerase 1 (Pin1) on renal ischemia-reperfusion (I/R) injury and underlying mechanism. METHODS: By establishing the in vitro and in vivo models of renal I/R, the role of Pin1 was explored by using molecular assays. RESULTS: In renal I/R,...

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Detalles Bibliográficos
Autores principales: Yu, Honglin, Jiang, Guanjun, Hu, Wei, Xu, Changgeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000979/
https://www.ncbi.nlm.nih.gov/pubmed/35416857
http://dx.doi.org/10.1590/acb370101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000979/
https://www.ncbi.nlm.nih.gov/pubmed/35416857
http://dx.doi.org/10.1590/acb370101

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