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Pin1 aggravates renal injury induced by ischemia and reperfusion in rats via Nrf2/HO-1 mediated endoplasmic reticulum stress
PURPOSE: To investigate the role of peptidyl-prolyl cis/trans isomerase 1 (Pin1) on renal ischemia-reperfusion (I/R) injury and underlying mechanism. METHODS: By establishing the in vitro and in vivo models of renal I/R, the role of Pin1 was explored by using molecular assays. RESULTS: In renal I/R,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000979/ https://www.ncbi.nlm.nih.gov/pubmed/35416857 http://dx.doi.org/10.1590/acb370101 |