Activation of LRP6 with HLY78 Attenuates Oxidative Stress and Neuronal Apoptosis via GSK3β/Sirt1/PGC-1α Pathway after ICH

BACKGROUND: Oxidative stress and neuronal apoptosis have important roles in the pathogenesis after intracerebral hemorrhage (ICH). Previous studies have reported that low-density lipoprotein receptor-related protein 6 (LRP6) exerts neuroprotection in several neurological diseases. Herein, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Peng, Qi, Dongqing, Cui, Yuhui, Lenahan, Cameron, Deng, Shuixiang, Tao, Xiaogen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001077/
https://www.ncbi.nlm.nih.gov/pubmed/35419167
http://dx.doi.org/10.1155/2022/7542468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001077/
https://www.ncbi.nlm.nih.gov/pubmed/35419167
http://dx.doi.org/10.1155/2022/7542468

Ejemplares similares