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Therapeutic Potential of CKD-504, a Novel Selective Histone Deacetylase 6 Inhibitor, in a Zebrafish Model of Neuromuscular Junction Disorders

The neuromuscular junction (NMJ), which is a synapse for signal transmission from motor neurons to muscle cells, has emerged as an important region because of its association with several peripheral neuropathies. In particular, mutations in GARS that affect the formation of NMJ result in Charcot-Mar...

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Detalles Bibliográficos
Autores principales: Jeong, Hui Su, Kim, Hye Jin, Kim, Deok-Ho, Chung, Ki Wha, Choi, Byung-Ok, Lee, Ji Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001154/
https://www.ncbi.nlm.nih.gov/pubmed/35356895
http://dx.doi.org/10.14348/molcells.2022.5005