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Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles

Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes. Dendrogenin A (DDA) is an endogenous tumour suppressor cholesterol‐derived metabolite. It is a new class of li...

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Detalles Bibliográficos
Autores principales: Record, Michel, Attia, Mehdi, Carayon, Kevin, Pucheu, Laly, Bunay, Julio, Soulès, Régis, Ayadi, Silia, Payré, Bruno, Perrin‐Cocon, Laure, Bourgailh, Florence, Lamazière, Antonin, Lotteau, Vincent, Poirot, Marc, Silvente‐Poirot, Sandrine, de Medina, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001168/
https://www.ncbi.nlm.nih.gov/pubmed/35411723
http://dx.doi.org/10.1002/jev2.12211