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Targeting the liver X receptor with dendrogenin A differentiates tumour cells to secrete immunogenic exosome‐enriched vesicles
Tumour cells are characterized by having lost their differentiation state. They constitutively secrete small extracellular vesicles (sEV) called exosomes when they come from late endosomes. Dendrogenin A (DDA) is an endogenous tumour suppressor cholesterol‐derived metabolite. It is a new class of li...
Autores principales: | Record, Michel, Attia, Mehdi, Carayon, Kevin, Pucheu, Laly, Bunay, Julio, Soulès, Régis, Ayadi, Silia, Payré, Bruno, Perrin‐Cocon, Laure, Bourgailh, Florence, Lamazière, Antonin, Lotteau, Vincent, Poirot, Marc, Silvente‐Poirot, Sandrine, de Medina, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001168/ https://www.ncbi.nlm.nih.gov/pubmed/35411723 http://dx.doi.org/10.1002/jev2.12211 |
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