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Conservation of the unusual dimeric JmjC fold of JMJD7 from Drosophila melanogaster to humans

The JmjC family of 2-oxoglutarate dependent oxygenases catalyse a range of hydroxylation and demethylation reactions in humans and other animals. Jumonji domain-containing 7 (JMJD7) is a JmjC (3S)-lysyl-hydroxylase that catalyses the modification of Developmentally Regulated GTP Binding Proteins 1 a...

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Detalles Bibliográficos
Autores principales: Chowdhury, Rasheduzzaman, Abboud, Martine I., Wiley, James, Tumber, Anthony, Markolovic, Suzana, Schofield, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001643/
https://www.ncbi.nlm.nih.gov/pubmed/35410347
http://dx.doi.org/10.1038/s41598-022-10028-y