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Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8(+) T-cell large granular lymphocytic leukemia

T cell large granular lymphocytic leukemia (T-LGLL) is a rare lymphoproliferative disorder of mature, clonally expanded T cells, where somatic-activating STAT3 mutations are common. Although T-LGLL has been described as a chronic T cell response to an antigen, the function of the non-leukemic immune...

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Detalles Bibliográficos
Autores principales: Huuhtanen, Jani, Bhattacharya, Dipabarna, Lönnberg, Tapio, Kankainen, Matti, Kerr, Cassandra, Theodoropoulos, Jason, Rajala, Hanna, Gurnari, Carmelo, Kasanen, Tiina, Braun, Till, Teramo, Antonella, Zambello, Renato, Herling, Marco, Ishida, Fumihiro, Kawakami, Toru, Salmi, Marko, Loughran, Thomas, Maciejewski, Jaroslaw P., Lähdesmäki, Harri, Kelkka, Tiina, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001660/
https://www.ncbi.nlm.nih.gov/pubmed/35411050
http://dx.doi.org/10.1038/s41467-022-29173-z