Targeted P2X7/NLRP3 signaling pathway against inflammation, apoptosis, and pyroptosis of retinal endothelial cells in diabetic retinopathy

Retinal endothelial cells (RECs) are the primary target cells for diabetes-induced vascular damage. The P2X7/NLRP3 pathway plays an essential role in amplifying inflammation via an ATP feedback loop, promoting the inflammatory response, pyroptosis, and apoptosis of RECs in the early stages of diabet...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Hui, Zhao, Hongran, Chen, Tianran, Song, Yanling, Cui, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001662/
https://www.ncbi.nlm.nih.gov/pubmed/35410316
http://dx.doi.org/10.1038/s41419-022-04786-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001662/
https://www.ncbi.nlm.nih.gov/pubmed/35410316
http://dx.doi.org/10.1038/s41419-022-04786-w

Ejemplares similares