Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells

T-cell large granular lymphocyte leukemia (T-LGLL) is a lymphoproliferative disease and bone marrow failure syndrome which responds to immunosuppressive therapies. We show single-cell TCR coupled with RNA sequencing of CD3(+) T cells from 13 patients, sampled before and after alemtuzumab treatments....

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Detalles Bibliográficos
Autores principales: Gao, Shouguo, Wu, Zhijie, Arnold, Bradley, Diamond, Carrie, Batchu, Sai, Giudice, Valentina, Alemu, Lemlem, Raffo, Diego Quinones, Feng, Xingmin, Kajigaya, Sachiko, Barrett, John, Ito, Sawa, Young, Neal S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001664/
https://www.ncbi.nlm.nih.gov/pubmed/35411048
http://dx.doi.org/10.1038/s41467-022-29175-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001664/
https://www.ncbi.nlm.nih.gov/pubmed/35411048
http://dx.doi.org/10.1038/s41467-022-29175-x

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