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Single-cell RNA sequencing coupled to TCR profiling of large granular lymphocyte leukemia T cells
T-cell large granular lymphocyte leukemia (T-LGLL) is a lymphoproliferative disease and bone marrow failure syndrome which responds to immunosuppressive therapies. We show single-cell TCR coupled with RNA sequencing of CD3(+) T cells from 13 patients, sampled before and after alemtuzumab treatments....
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001664/ https://www.ncbi.nlm.nih.gov/pubmed/35411048 http://dx.doi.org/10.1038/s41467-022-29175-x |