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Identification of lamprey variable lymphocyte receptors that target the brain vasculature

The blood–brain barrier (BBB) represents a significant bottleneck for the delivery of therapeutics to the central nervous system. In recent years, the promise of coopting BBB receptor-mediated transport systems for brain drug delivery has increased in large part due to the discovery and engineering...

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Detalles Bibliográficos
Autores principales: Lajoie, Jason M., Katt, Moriah E., Waters, Elizabeth A., Herrin, Brantley R., Shusta, Eric V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001667/
https://www.ncbi.nlm.nih.gov/pubmed/35411012
http://dx.doi.org/10.1038/s41598-022-09962-8