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Mucin 21 confers resistance to apoptosis in an O-glycosylation-dependent manner

Highly glycosylated mucins protect epithelial surfaces from external insults and are related to malignant behaviors of carcinoma cells. However, the importance of carbohydrate chains on mucins in the process of cellular protection is not fully understood. Here, we investigated the effect of human mu...

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Detalles Bibliográficos
Autores principales: Tian, Yuan, Denda-Nagai, Kaori, Tsukui, Tatsuya, Ishii-Schrade, Katrin B., Okada, Kyoko, Nishizono, Yoshihiro, Matsuzaki, Kosuke, Hafley, Margarete, Bresalier, Robert S., Irimura, Tatsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001685/
https://www.ncbi.nlm.nih.gov/pubmed/35410995
http://dx.doi.org/10.1038/s41420-022-01006-4