Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation

Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator required for gene silencing during development. Although PRC2 is a well-established RNA-binding complex, the biological function of PRC2-RNA interaction has been controversial. Here, we study the gene-regulatory role of the inhibitory P...

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Detalles Bibliográficos
Autores principales: Teo, Wei Wen, Cao, Xinang, Wu, Chan-Shuo, Tan, Hong Kee, Zhou, Qiling, Gao, Chong, Vanuytsel, Kim, Kumar, Sara S., Murphy, George J., Yang, Henry, Chai, Li, Tenen, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001699/
https://www.ncbi.nlm.nih.gov/pubmed/35411071
http://dx.doi.org/10.1038/s42003-022-03250-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001699/
https://www.ncbi.nlm.nih.gov/pubmed/35411071
http://dx.doi.org/10.1038/s42003-022-03250-x

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