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Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation
Polycomb Repressive Complex 2 (PRC2) is an epigenetic regulator required for gene silencing during development. Although PRC2 is a well-established RNA-binding complex, the biological function of PRC2-RNA interaction has been controversial. Here, we study the gene-regulatory role of the inhibitory P...
Autores principales: | Teo, Wei Wen, Cao, Xinang, Wu, Chan-Shuo, Tan, Hong Kee, Zhou, Qiling, Gao, Chong, Vanuytsel, Kim, Kumar, Sara S., Murphy, George J., Yang, Henry, Chai, Li, Tenen, Daniel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001699/ https://www.ncbi.nlm.nih.gov/pubmed/35411071 http://dx.doi.org/10.1038/s42003-022-03250-x |
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