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NAMPT-dependent NAD(+) salvage is crucial for the decision between apoptotic and necrotic cell death under oxidative stress

Oxidative stress is a state in which the accumulation of reactive oxygen species exceeds the capacity of cellular antioxidant systems. Both apoptosis and necrosis are observed under oxidative stress, and we have reported that these two forms of cell death are induced in H(2)O(2)-stimulated HeLa cell...

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Detalles Bibliográficos
Autores principales: Nishida, Takuto, Naguro, Isao, Ichijo, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001718/
https://www.ncbi.nlm.nih.gov/pubmed/35410407
http://dx.doi.org/10.1038/s41420-022-01007-3