Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity

The binding of influenza hemagglutinin (HA) to sialic acid (SA) receptors plays a well-defined role in shaping infection but the impact of such binding on vaccine responses has not yet been explored. We generated a virus-like particle (VLP) vaccine bearing the HA of H1N1 A/California/07/09 that is u...

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Detalles Bibliográficos
Autores principales: Hendin, Hilary E., Lavoie, Pierre-Olivier, Gravett, Jason M., Pillet, Stéphane, Saxena, Pooja, Landry, Nathalie, D’Aoust, Marc-André, Ward, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001741/
https://www.ncbi.nlm.nih.gov/pubmed/35410323
http://dx.doi.org/10.1038/s41541-022-00463-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001741/
https://www.ncbi.nlm.nih.gov/pubmed/35410323
http://dx.doi.org/10.1038/s41541-022-00463-3

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