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Genome-Wide Knockout Screen Identifies EGLN3 Involving in Ammonia Neurotoxicity

Hepatic encephalopathy (HE) is a brain dysfunction associated with poor quality of life, increased morbidity and mortality. The pathogenesis of HE is still not fully clarified and effective therapeutic strategies are imperative. Among multiple factors that contribute to the pathophysiological proces...

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Detalles Bibliográficos
Autores principales: Li, Jiequn, Chen, Chunli, Li, Chenchen, Hu, Zhiping, Tan, Jieqiong, Zeng, Liuwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001847/
https://www.ncbi.nlm.nih.gov/pubmed/35425766
http://dx.doi.org/10.3389/fcell.2022.820692