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The edoxaban‐M4 metabolite and measurement of edoxaban by chromogenic assays in human plasma

INTRODUCTION: Edoxaban is the only anti‐Xa inhibitor metabolized in pharmacologically active moiety that could interfere with chromogenic anti‐Xa assays, especially in case of drug‐drug interactions or physiological disorders. MATERIALS AND METHODS: We evaluated the contribution of the main metaboli...

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Detalles Bibliográficos
Autores principales: Siriez, Romain, Yildiz, Halil, Bouvy, Céline, Haguet, Hélène, Maloteau, Vincent, Hardy, Michaël, Mullier, François, Dogné, Jean‐Michel, Hainaut, Philippe, Douxfils, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001858/
https://www.ncbi.nlm.nih.gov/pubmed/35434470
http://dx.doi.org/10.1002/rth2.12680