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Protease‐activated receptor antagonists prevent thrombosis when dual antiplatelet therapy is insufficient in an occlusive thrombosis microfluidic model

BACKGROUND: Platelet activation and arterial thrombosis on a ruptured atherosclerotic plaque is a major cause of myocardial infarction. Dual antiplatelet therapy (DAPT), the combination of platelet aggregation inhibitors, aspirin and a P2Y(12) antagonist, is used to prevent arterial thrombosis. Howe...

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Detalles Bibliográficos
Autores principales: Berry, Jess, Harper, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001860/
https://www.ncbi.nlm.nih.gov/pubmed/35434469
http://dx.doi.org/10.1002/rth2.12703