Determining the Effects of Differential Expression of GRKs and β-arrestins on CLR-RAMP Agonist Bias

Signalling of the calcitonin-like receptor (CLR) is multifaceted, due to its interaction with receptor activity modifying proteins (RAMPs), and three endogenous peptide agonists. Previous studies have focused on the bias of G protein signalling mediated by the receptor and receptor internalisation o...

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Detalles Bibliográficos
Autores principales: Pearce, Abigail, Redfern-Nichols, Theo, Harris, Matthew, Poyner, David R., Wigglesworth, Mark, Ladds, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001978/
https://www.ncbi.nlm.nih.gov/pubmed/35422711
http://dx.doi.org/10.3389/fphys.2022.840763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001978/
https://www.ncbi.nlm.nih.gov/pubmed/35422711
http://dx.doi.org/10.3389/fphys.2022.840763

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