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Determining the Effects of Differential Expression of GRKs and β-arrestins on CLR-RAMP Agonist Bias
Signalling of the calcitonin-like receptor (CLR) is multifaceted, due to its interaction with receptor activity modifying proteins (RAMPs), and three endogenous peptide agonists. Previous studies have focused on the bias of G protein signalling mediated by the receptor and receptor internalisation o...
Autores principales: | Pearce, Abigail, Redfern-Nichols, Theo, Harris, Matthew, Poyner, David R., Wigglesworth, Mark, Ladds, Graham |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001978/ https://www.ncbi.nlm.nih.gov/pubmed/35422711 http://dx.doi.org/10.3389/fphys.2022.840763 |
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