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Comparison of the copy-neutral loss of heterozygosity identified from whole-exome sequencing data using three different tools
Loss of heterozygosity (LOH) is a genomic aberration. In some cases, LOH can be generated without changing the copy number, which is called copy-neutral LOH (CN-LOH). CN-LOH frequently occurs in various human diseases, including cancer. However, the biological and clinical implications of CN-LOH for...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Korea Genome Organization
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9001996/ https://www.ncbi.nlm.nih.gov/pubmed/35399003 http://dx.doi.org/10.5808/gi.21066 |