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Exploration of errors in variance caused by using the first-order approXimation in Mendelian randomization

Mendelian randomization (MR) uses genetic variation as a natural experiment to investigate the causal effects of modifiable risk factors (exposures) on outcomes. Two-sample Mendelian randomization (2SMR) is widely used to measure causal effects between exposures and outcomes via genome-wide associat...

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Detalles Bibliográficos
Autores principales: Kim, Hakin, Kim, Kunhee, Han, Buhm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002003/
https://www.ncbi.nlm.nih.gov/pubmed/35399008
http://dx.doi.org/10.5808/gi.21060