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The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster

Silencing of transposable elements (TEs) by Piwi-interacting RNAs (piRNAs) is crucial for maintaining germline genome integrity and fertility in animals. To repress TEs, PIWI clade Argonaute proteins cooperate with several Tudor domain-containing (Tdrd) proteins at membraneless perinuclear organelle...

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Detalles Bibliográficos
Autores principales: Lim, Lin-Xenia, Isshiki, Wakana, Iki, Taichiro, Kawaguchi, Shinichi, Kai, Toshie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002060/
https://www.ncbi.nlm.nih.gov/pubmed/35425810
http://dx.doi.org/10.3389/fmolb.2022.818302