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Expression of a RhoA-Specific Guanine Nucleotide Exchange Factor, p190RhoGEF, in Mouse Macrophages Negatively Affects M1 Polarization and Inflammatory Responses

A RhoA-specific guanine nucleotide exchange factor, p190RhoGEF, was first cloned and identified in neuronal cells. In immune cells, we first reported the role of p190RhoGEF in B cells: expression of p190RhoGEF increased after CD40 stimulation and was required for CD40-mediated B cell activation and...

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Detalles Bibliográficos
Autores principales: Choi, So-Yeon, Ahn, Yu Ri, Lee, Eun-Bi, Yu, Mi Jin, Lee, Jong Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002135/
https://www.ncbi.nlm.nih.gov/pubmed/35422804
http://dx.doi.org/10.3389/fimmu.2022.782475