An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin

Aureolysin, a secreted metallopeptidase (MP) from the thermolysin family, functions as a major virulence factor in Staphylococcus aureus. No specific aureolysin inhibitors have yet been described, making this an important target for the development of novel antimicrobial drugs in times of rampant an...

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Detalles Bibliográficos
Autores principales: Mendes, Soraia R., Eckhard, Ulrich, Rodríguez-Banqueri, Arturo, Guevara, Tibisay, Czermak, Peter, Marcos, Enrique, Vilcinskas, Andreas, Gomis-Rüth, F. Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002140/
https://www.ncbi.nlm.nih.gov/pubmed/35465156
http://dx.doi.org/10.1016/j.csbj.2022.01.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002140/
https://www.ncbi.nlm.nih.gov/pubmed/35465156
http://dx.doi.org/10.1016/j.csbj.2022.01.001

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