Cargando…

ATP13A2 protects dopaminergic neurons in Parkinson's disease: from biology to pathology

As a late endosomal/lysosomal transport protein of the P5-type, ATP13A2 is capable of removing the abnormal accumulation of α-synuclein, which maintains the homeostasis of metal ions and polyamines in the central nervous system. Furthermore, ATP13A2 regulates the normal function of several organelle...

Descripción completa

Detalles Bibliográficos
Autores principales: Dang, Tao, Cao, Wen-Jing, Zhao, Rong, Lu, Ming, Hu, Gang, Qiao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002154/
https://www.ncbi.nlm.nih.gov/pubmed/35387901
http://dx.doi.org/10.7555/JBR.36.20220001