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Polygonum cuspidatum Extract (Pc-Ex) Containing Emodin Suppresses Lung Cancer-Induced Cachexia by Suppressing TCF4/TWIST1 Complex-Induced PTHrP Expression

Cachexia, which is characterised by the wasting of fat and skeletal muscles, is the most common risk factor for increased mortality rates among patients with advanced lung cancer. PTHLH (parathyroid hormone-like hormone) is reported to be involved in the pathogenesis of cancer cachexia. However, the...

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Detalles Bibliográficos
Autores principales: Fang, Xue-Quan, Kim, Young-Seon, Lee, Yoon-Mi, Lee, Mingyu, Lim, Woo-Jin, Yim, Woo-Jong, Han, Min-Woo, Lim, Ji-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002362/
https://www.ncbi.nlm.nih.gov/pubmed/35406121
http://dx.doi.org/10.3390/nu14071508