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Pathogenic Leptospira Evolved a Unique Gene Family Comprised of Ricin B-Like Lectin Domain-Containing Cytotoxins

Leptospirosis is a globally important neglected zoonotic disease. Previous data suggest that a family of virulence-modifying (VM) proteins (PF07598) is a distinctive feature of group I pathogenic Leptospira that evolved as important virulence determinants. Here, we show that one such VM protein, LA3...

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Detalles Bibliográficos
Autores principales: Chaurasia, Reetika, Marroquin, Alan S., Vinetz, Joseph M., Matthias, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002632/
https://www.ncbi.nlm.nih.gov/pubmed/35422779
http://dx.doi.org/10.3389/fmicb.2022.859680