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African derived phytocompounds may interfere with SARS-CoV-2 RNA capping machinery via inhibition of 2′-O-ribose methyltransferase: An in silico perspective

Despite the ongoing vaccination against the life-threatening COVID-19, there is need for viable therapeutic interventions. The S-adenosyl-l-Methionine (SAM) dependent 2-O’-ribose methyltransferase (2′-O-MTase) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a therapeutic...

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Detalles Bibliográficos
Autores principales: Gyebi, Gideon A., Ogunyemi, Oludare M., Adefolalu, Adedotun A., Rodríguez-Martínez, Alejandro, López-Pastor, Juan F., Banegas-Luna, Antonio J., Pérez-Sánchez, Horacio, Adegunloye, Adegbenro P., Ogunro, Olalekan B., Afolabi, Saheed O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002684/
https://www.ncbi.nlm.nih.gov/pubmed/35431328
http://dx.doi.org/10.1016/j.molstruc.2022.133019