Synthetic Sulfated Polymers Control Amyloid Aggregation of Ovine Prion Protein and Decrease Its Toxicity

Amyloid aggregation, including aggregation and propagation of prion protein, is a key factor in numerous human diseases, so-called amyloidosis, with a very poor ability for treatment or prevention. The present work describes the effect of sulfated or sulfonated polymers (sodium dextran sulfate, poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Semenyuk, Pavel, Evstafyeva, Diana, Izumrudov, Vladimir, Muronetz, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002794/
https://www.ncbi.nlm.nih.gov/pubmed/35406350
http://dx.doi.org/10.3390/polym14071478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002794/
https://www.ncbi.nlm.nih.gov/pubmed/35406350
http://dx.doi.org/10.3390/polym14071478

Ejemplares similares