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Synthetic Sulfated Polymers Control Amyloid Aggregation of Ovine Prion Protein and Decrease Its Toxicity

Amyloid aggregation, including aggregation and propagation of prion protein, is a key factor in numerous human diseases, so-called amyloidosis, with a very poor ability for treatment or prevention. The present work describes the effect of sulfated or sulfonated polymers (sodium dextran sulfate, poly...

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Detalles Bibliográficos
Autores principales:	Semenyuk, Pavel, Evstafyeva, Diana, Izumrudov, Vladimir, Muronetz, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002794/ https://www.ncbi.nlm.nih.gov/pubmed/35406350 http://dx.doi.org/10.3390/polym14071478

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