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NANOS3 suppresses premature spermatogonial differentiation to expand progenitors and fine-tunes spermatogenesis in mice

In the mouse testis, sperm originate from spermatogonial stem cells (SSCs). SSCs give rise to spermatogonial progenitors, which expand their population until entering the differentiation process that is precisely regulated by a fixed time-scaled program called the seminiferous cycle. Although this e...

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Detalles Bibliográficos
Autores principales: Inoue, Hiroki, Sakurai, Takayuki, Hasegawa, Kazuteru, Suzuki, Atsushi, Saga, Yumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002807/
https://www.ncbi.nlm.nih.gov/pubmed/35394008
http://dx.doi.org/10.1242/bio.059146