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The importance of considering regulatory domains in genome-wide analyses – the nearest gene is often wrong!
The expression of a large number of genes is regulated by regulatory elements that are located far away from their promoters. Identifying which gene is the target of a specific regulatory element or is affected by a non-coding mutation is often accomplished by assigning these regions to the nearest...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002814/ https://www.ncbi.nlm.nih.gov/pubmed/35377406 http://dx.doi.org/10.1242/bio.059091 |