Elimination of Vitamin D Signaling Causes Increased Mortality in a Model of Overactivation of the Insulin Receptor: Role of Lipid Metabolism

Vitamin D (VD) deficiency has been associated with cancer and diabetes. Insulin signaling through the insulin receptor (IR) stimulates cellular responses by activating the PI3K/AKT pathway. PTEN is a tumor suppressor and a negative regulator of the pathway. Its absence enhances insulin signaling lea...

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Detalles Bibliográficos
Autores principales: Crespo-Masip, Maria, Perez-Gomez, Aurora, Garcia-Carrasco, Alicia, Jover, Ramiro, Guzmán, Carla, Dolcet, Xavier, Ibarz, Mercé, Martínez, Cristina, Eritja, Àuria, Diaz-Tocados, Juan Miguel, Valdivielso, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002971/
https://www.ncbi.nlm.nih.gov/pubmed/35406129
http://dx.doi.org/10.3390/nu14071516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9002971/
https://www.ncbi.nlm.nih.gov/pubmed/35406129
http://dx.doi.org/10.3390/nu14071516

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