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A Novel Aminomethacrylate-Based Copolymer for Solubility Enhancement—From Radical Polymer Synthesis to Manufacture and Characterization of Amorphous Solid Dispersions

The present study covers the synthesis, purification and evaluation of a novel aminomethacrylate-based copolymer in terms of its suitability for improving the solubility and in vitro release of poorly water-soluble drug compounds. The new copolymer was synthesized by solvent polymerization with radi...

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Detalles Bibliográficos
Autores principales: Schmied, Fabian-Pascal, Bernhardt, Alexander, Moers, Christian, Meier, Christian, Endres, Thomas, Klein, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003068/
https://www.ncbi.nlm.nih.gov/pubmed/35406157
http://dx.doi.org/10.3390/polym14071281