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Stop of proton-pump inhibitor treatment in patients with liver cirrhosis (STOPPIT): study protocol for a prospective, multicentre, controlled, randomized, double-blind trial

BACKGROUND: Proton-pump inhibitors (PPI) are liberally prescribed in patients with liver cirrhosis. Observational studies link PPI therapy in cirrhotic patients with an increased risk for infectious complications, hepatic encephalopathy and an increased risk for hospitalization and mortality. Howeve...

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Detalles Bibliográficos
Autores principales: Wehmeyer, Malte H., Horvatits, Thomas, Buchholz, Anika, Krause, Linda, Walter, Sarah, Zapf, Antonia, Lohse, Ansgar W., Kluwe, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9003168/
https://www.ncbi.nlm.nih.gov/pubmed/35414106
http://dx.doi.org/10.1186/s13063-022-06232-w